Wnt, Beta-Catenin, TCF
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Was ist das | |
Struktur | |
Physiologie | |
Knockout | |
Transgen | |
Mutation | |
Polymorphismus | |
Genexpression | |
Inhibitoren | |
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1 Bibliographie
- ↑ Interaction of nuclear receptors with the Wnt/beta-catenin/Tcf signaling axis: Wnt you like to know? Endocr Rev 26(7):898-915 (2005) PMID 16126938
- ↑ Mechanistic insights from structural studies of beta-catenin and its binding partners. J Cell Sci 120(Pt 19):3337-44 (2007) PMID 17881495
- ↑ Wnt signalling: variety at the core. J Cell Sci 120(Pt 3):385-93 (2007) PMID 17251379
- ↑ Wnt signaling: complexity at the surface. J Cell Sci 119(Pt 3):395-402 (2006) PMID 16443747
- ↑ Secreted antagonists of the Wnt signalling pathway. J Cell Sci 116(Pt 13):2627-34 (2003) PMID 12775774
- ↑ Plakoglobin and beta-catenin: protein interactions, regulation and biological roles. J Cell Sci 113 ( Pt 18)():3127-39 (2000) PMID 10954412
- ↑ Antiangiogenesis to treat cancer and intraocular neovascular disorders. Lab Invest 87(3):227-30 (2007) PMID 17259997
- ↑ To beta or not to beta: canonical beta-catenin signaling pathway and ovarian development. Dev Dyn 237(12):3672-80 (2008) PMID 18985752
- ↑ The Wnt connection to tumorigenesis. Int J Dev Biol 48(5-6):477-87 (2004) PMID 15349822
- ↑ A tight control over Wnt action. Int J Dev Biol 43(7):675-80 (1999) PMID 10668977
- ↑ Wnt signal transduction pathways. Organogenesis 4(2):68-75 (2008) PMID 19279717
- ↑ Wnt signaling in kidney development and disease. Organogenesis 4(2):55-9 (2008) PMID 19279716
- ↑ 13,0 13,1 Wnt signaling: an essential regulator of cardiovascular differentiation, morphogenesis and progenitor self-renewal. Development 135(5):789-98 (2008) PMID 18263841
- ↑ 14,0 14,1 The making of Wnt: new insights into Wnt maturation, sorting and secretion. Development 134(1):3-12 (2007) PMID 17138665
- ↑ 15,0 15,1 Wnts and Hedgehogs: lipid-modified proteins and similarities in signaling mechanisms at the cell surface. Development 130(22):5297-305 (2003) PMID 14530294
- ↑ Catenins: keeping cells from getting their signals crossed. Dev Cell 11(5):601-12 (2006) PMID 17084354
- ↑ Wnt signaling and the activation of myogenesis in mammals. EMBO J 18(24):6867-72 (1999) PMID 10601008
- ↑ Regulation of Wnt protein secretion and its role in gradient formation. EMBO Rep 9(10):977-82 (2008) PMID 18787559
- ↑ Wnt pathway: a new role in regulation of inflammation. Arterioscler Thromb Vasc Biol 28(3):400-2 (2008) PMID 18296599
- ↑ Canonical WNT signalling controls hair follicle spacing. Cell Adh Migr 1(3):149-51 (2007) PMID 19262137
- ↑ Re-evaluating the role of Frat in Wnt-signal transduction. Cell Cycle 4(8):1065-72 (2005) PMID 16082208
- ↑ Beta-catenin nuclear activation: common pathway between Wnt and growth factor signaling in vascular smooth muscle cell proliferation? Circ Res 99(12):1287-9 (2006) PMID 17158343
- ↑ Wnt/Notch signalling and information processing during development. Development 135(3):411-24 (2008) PMID 18192283
- ↑ LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131(8):1663-77 (2004) PMID 15084453
- ↑ Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression. EMBO Rep 1(1):24-8 (2000) PMID 11256619
- ↑ Pathophysiological aspects of Wnt-signaling in endocrine disease. Eur J Endocrinol 160(5):731-7 (2009) PMID 19246555
- ↑ Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev 22(17):2308-41 (2008) PMID 18765787
- ↑ Wnt signaling: is the party in the nucleus? Genes Dev 20(11):1394-404 (2006) PMID 16751178
- ↑ CKI, there's more than one: casein kinase I family members in Wnt and Hedgehog signaling. Genes Dev 20(4):399-410 (2006) PMID 16481469
- ↑ Wnt signaling in the intestinal epithelium: from endoderm to cancer. Genes Dev 19(8):877-90 (2005) PMID 15833914
- ↑ Wnt signaling and cancer. Genes Dev 14(15):1837-51 (2000) PMID 10921899
- ↑ Wnt signaling: a common theme in animal development. Genes Dev 11(24):3286-305 (1997) PMID 9407023
- ↑ Signal transduction through beta-catenin and specification of cell fate during embryogenesis. Genes Dev 10(20):2527-39 (1996) PMID 8895655
- ↑ Canonical Wnt signaling: high-throughput RNAi widens the path. Genome Biol 6(9):231 (2005) PMID 16168092
- ↑ The Wnts. Genome Biol 3(1):REVIEWS3001 (2002) PMID 11806834
- ↑ Wnt signaling in polycystic kidney disease. J Am Soc Nephrol 18(5):1389-98 (2007) PMID 17429050
- ↑ Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 281(32):22429-33 (2006) PMID 16793760
- ↑ Sclerostin and Wnt signaling--the pathway to bone strength. J Clin Endocrinol Metab 90(12):6741-3 (2005) PMID 16330810
- ↑ Wnt signaling in neural circuit development. J Neurosci 25(45):10376-8 (2005) PMID 16280576
- ↑ The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus. Mol Endocrinol 22(11):2383-92 (2008) PMID 18599616
- ↑ Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism. Mol Endocrinol 21(11):2605-14 (2007) PMID 17622581
- ↑ Wnt/beta-catenin signaling in development and disease. Cell 127(3):469-80 (2006) PMID 17081971
- ↑ A dedicated Wnt secretion factor. Cell 125(3):432-3 (2006) PMID 16678089
- ↑ Wnt pathway activation: new relations and locations. Cell 120(1):11-4 (2005) PMID 15652476
- ↑ Linking colorectal cancer to Wnt signaling. Cell 103(2):311-20 (2000) PMID 11057903
- ↑ Wnts as retrograde signals for axon and growth cone differentiation. Cell 100(5):495-7 (2000) PMID 10721986
- ↑ Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 88(6):725-8 (1997) PMID 9118212
- ↑ beta-Catenin: a pivot between cell adhesion and Wnt signalling. Curr Biol 15(2):R64-7 (2005) PMID 15668160
- ↑ Heads or tails: Wnts and anterior-posterior patterning. Curr Biol 11(17):R713-24 (2001) PMID 11553348
- ↑ Wnt signaling: an embarrassment of receptors. Curr Biol 10(24):R919-22 (2000) PMID 11137030
- ↑ Wnt signaling: Moving in a new direction. Curr Biol 10(15):R562-4 (2000) PMID 10959830
- ↑ Wnt signalling shows its versatility. Curr Biol 9(18):R684-7 (1999) PMID 10508601
- ↑ Wingless signaling: the inconvenient complexities of life. Curr Biol 8(4):R140-4 (1998) PMID 9501979
- ↑ A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling. Dev Cell 5(3):367-77 (2003) PMID 12967557
- ↑ A Wnt-Wnt situation. Dev Cell 4(6):791-7 (2003) PMID 12791265
- ↑ WNT/beta-catenin signaling in liver health and disease. Hepatology 45(5):1298-305 (2007) PMID 17464972
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