Riluzol

Entstehender Artikel

Siehe auch
Freie Übersichtsartikel	^[1] ^[2]^[3] ^[4]^[5]^[6]
Wichtige Übersichtsartikel	^[7]
Medline Suchterm/ Synonyme
Was ist das
Struktur	6-(Trifluormethoxy)-1,3-benzothiazol-2-amin
Physiologie
Knockout
Transgen
Mutation
Polymorphismus
Genexpression
Inhibitoren
Agonisten

1 Bibliographie

↑ Riluzole enhances the anti-seizure action of conventional antiepileptic drugs against pentetrazole-induced convulsions in mice Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity Molecular Psychiatry 7:726- 733 (2002)
↑ Mizoule J, Meldrum B, Mazadier M, Croucher M, Ollat C, Uzan A et al. 2-Amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid transmission I anticonvulsant properties. Neuropharmacology 1995; 24: 767-773 Abstracts
↑ Blockade of Persistent Sodium Currents Contributes to the Riluzole-Induced Inhibition of Spontaneous Activity and Oscillations in Injured DRG Neurons PLoS ONE 6(4): e18681. doi:10.1371/journal.pone.0018681
↑ [http://chrisparsons.de/Chris/Acrobat/Rammes_2008_18493706.pdf The fraction of activated N-methyl-D-Aspartate receptors during synaptic transmission remains constant in the presence of the glutamate release inhibitor riluzole J Neural Transm (2008) 115:1119–1126]
↑ Glutamatergic Modulators: The Future of Treating Mood Disorders? Harv Rev Psychiatry. 2010 October ; 18(5): 293–303. doi:10.3109/10673229.2010.511059.
↑ Anticonvulsant and sleep-waking influences of riluzole in a rat model of absence epilepsy European J Pharmcol. 199 371 373 (1991)
↑ Duprat et al The Neuroprotective Agent Riluzole Activates the Two P Domain K+ Channels TREK-1 and TRAAK Molecular Pharmacology 57:906-912 (2000)